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Gilead’s Hypertension Drug Meets Primary Endpoints

Gilead Sciences' Phase III DAR-311 (DORADO) study evaluating its endothelin receptor antagonist (ERA) darusentan for the treatment of resistant hypertension, met its co-primary efficacy endpoints.

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Gilead Sciences’ Phase III DAR-311 (DORADO) study evaluating its endothelin receptor antagonist (ERA) darusentan for the treatment of resistant hypertension, met its co-primary efficacy endpoints. DORADO is one of two ongoing Phase III trials evaluating the safety, efficacy and tolerability of darusentan as an add-on treatment for resistant hypertension. The second study, DAR-312 (DORADO-AC), is expected to be complete by the end of this year. In the DAR-311 study, reductions in mean tr...

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